Description

1. Product Overview: Tirzide 10® is a dual incretin receptor agonist formulation containing Tirzepatide, designed to improve glycemic control in adults with type 2 diabetes mellitus and support weight management under medical supervision.
2. Composition: Tirzepatide INN 10 mg / 0.5 mL | Dosage Form: Injection
3. Pharmacological Class: Dual GIP and GLP-1 Receptor Agonist
4. Mechanism of Action: Tirzepatide activates both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, enhancing insulin secretion, reducing glucagon levels, slowing gastric emptying, and decreasing appetite.
5. Indications: Type 2 diabetes mellitus | Adjunct to diet and exercise for glycemic control | Weight management support in eligible patients
6. Dosage & Administration: As directed by physician only | Subcutaneous injection | Dose titration required based on clinical response
7. Clinical Benefits: Improves blood glucose control | Supports significant weight reduction | Reduces appetite | Improves metabolic health markers
8. Contraindications: Hypersensitivity to Tirzepatide or any component of the formulation | Personal or family history of medullary thyroid carcinoma | Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
9. Precautions: Risk of pancreatitis | Monitor renal function in susceptible patients | Not indicated for type 1 diabetes | Use only under strict medical supervision
10. Drug Interactions: May delay absorption of oral medications due to slowed gastric emptying | Caution when used with insulin or sulfonylureas (risk of hypoglycemia)
11. Special Populations: Not recommended during pregnancy or lactation unless clearly advised by physician | Use in elderly under medical supervision
12. Adverse Effects: Nausea | Vomiting | Diarrhea | Decreased appetite | Abdominal discomfort | Rare risk of pancreatitis
13. Storage Conditions: Store in refrigerator (2°C to 8°C) | Do not freeze | Protect from light | Keep out of reach of children
14. Packaging: Prefilled injection pen / vial (as available)
15. Manufacturer: Everest Pharmaceutical Ltd.