Description
- Product Overview: Mezoxia® is a progestational agent containing Megestrol Acetate, used primarily for appetite stimulation and management of cachexia associated with chronic illness or cancer.
- Composition: Megestrol Acetate 160 mg | Dosage Form: Tablet
- Pharmacological Class: Progestin / Appetite Stimulant Agent
- Mechanism of Action: Megestrol acetate acts as a synthetic progestin that influences appetite regulation in the hypothalamus and has anti-cytokine effects, leading to increased appetite and weight gain.
- Indications: Cancer-related cachexia | HIV-associated weight loss | Unintentional weight loss in chronic illness | Appetite stimulation in selected cases
- Dosage & Administration: As directed by physician only | Oral use | Dose and duration depend on clinical condition | Usually taken once daily
- Clinical Benefits: Improves appetite | Promotes weight gain | Enhances nutritional status | Supports quality of life in chronic illness
- Contraindications: Hypersensitivity to Megestrol Acetate or any component | Pregnancy (contraindicated)
- Precautions: Risk of thromboembolic events | Use cautiously in diabetic patients | May cause fluid retention | Long-term use requires monitoring
- Drug Interactions: May interact with anticoagulants and other hormonal therapies
- Special Populations: Not recommended during pregnancy | Use in elderly and debilitated patients under strict medical supervision
- Adverse Effects: Weight gain | Increased appetite | Edema | Nausea | Risk of thromboembolism (rare but serious)
- Storage Conditions: Store below 30°C | Protect from light and moisture | Keep out of reach of children
- Packaging: Tablet blister pack
- Manufacturer: Everest Pharmaceutical Ltd.
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