{"id":99,"date":"2026-04-14T15:48:22","date_gmt":"2026-04-14T15:48:22","guid":{"rendered":"https:\/\/asceticit.shop\/wp2\/?post_type=product&#038;p=99"},"modified":"2026-04-23T19:33:43","modified_gmt":"2026-04-23T19:33:43","slug":"osimert","status":"publish","type":"product","link":"https:\/\/asceticit.shop\/wp2\/product\/osimert\/","title":{"rendered":"Osimert"},"content":{"rendered":"<p><strong data-start=\"808\" data-end=\"832\">1. Product Overview:<\/strong> Osimert is a tablet formulation of Osimertinib INN 80 mg, a third-generation EGFR tyrosine kinase inhibitor used in the treatment of non-small cell lung cancer (NSCLC) with specific EGFR mutations, including T790M mutation.<br data-start=\"1056\" data-end=\"1059\" \/><strong data-start=\"1059\" data-end=\"1078\">2. Composition:<\/strong> Active Ingredient: Osimertinib INN 80 mg | Dosage Form: Tablet<br data-start=\"1141\" data-end=\"1144\" \/><strong data-start=\"1144\" data-end=\"1173\">3. Pharmacological Class:<\/strong> EGFR (Epidermal Growth Factor Receptor) Tyrosine Kinase Inhibitor<br data-start=\"1239\" data-end=\"1242\" \/><strong data-start=\"1242\" data-end=\"1269\">4. Mechanism of Action:<\/strong> Osimertinib selectively and irreversibly inhibits EGFR mutations, including T790M resistance mutation, leading to inhibition of cancer cell signaling pathways, reduced tumor growth, and apoptosis of cancer cells.<br data-start=\"1482\" data-end=\"1485\" \/><strong data-start=\"1485\" data-end=\"1504\">5. Indications:<\/strong> EGFR mutation-positive locally advanced or metastatic non-small cell lung cancer (NSCLC) | T790M mutation-positive NSCLC<br data-start=\"1625\" data-end=\"1628\" data-is-only-node=\"\" \/><strong data-start=\"1628\" data-end=\"1659\">6. Dosage &amp; Administration:<\/strong> As prescribed by oncologist | Oral use | Once daily dose | Can be taken with or without food<br data-start=\"1752\" data-end=\"1755\" \/><strong data-start=\"1755\" data-end=\"1780\">7. Clinical Benefits:<\/strong> Targets EGFR mutations selectively | Effective in resistant NSCLC cases | Slows disease progression | Improves survival outcomes<br data-start=\"1909\" data-end=\"1912\" \/><strong data-start=\"1912\" data-end=\"1937\">8. Contraindications:<\/strong> Hypersensitivity to Osimertinib or any component<br data-start=\"1986\" data-end=\"1989\" \/><strong data-start=\"1989\" data-end=\"2008\">9. Precautions:<\/strong> Monitor lung, liver, and heart function | Risk of interstitial lung disease | Use under specialist supervision<br data-start=\"2119\" data-end=\"2122\" \/><strong data-start=\"2122\" data-end=\"2148\">10. Drug Interactions:<\/strong> CYP3A4 inducers (rifampicin, carbamazepine) may reduce effectiveness | CYP3A inhibitors may increase exposure<br data-start=\"2258\" data-end=\"2261\" \/><strong data-start=\"2261\" data-end=\"2289\">11. Special Populations:<\/strong> Pregnancy contraindicated | Lactation not recommended | Dose adjustment may be required in hepatic impairment<br data-start=\"2399\" data-end=\"2402\" \/><strong data-start=\"2402\" data-end=\"2426\">12. Adverse Effects:<\/strong> Diarrhea | Rash | Dry skin | Fatigue | Reduced appetite<br data-start=\"2482\" data-end=\"2485\" \/><strong data-start=\"2485\" data-end=\"2512\">13. Storage Conditions:<\/strong> Store below 30\u00b0C | Protect from moisture and light | Keep out of reach of children<br data-start=\"2595\" data-end=\"2598\" \/><strong data-start=\"2598\" data-end=\"2616\">14. Packaging:<\/strong> Tablet in blister pack<br data-start=\"2639\" data-end=\"2642\" \/><strong data-start=\"2642\" data-end=\"2663\">15. Manufacturer:<\/strong> Everest Pharmaceutical Ltd.<\/p>\n","protected":false},"excerpt":{"rendered":"<p data-start=\"196\" data-end=\"434\"><strong data-start=\"196\" data-end=\"208\">Osimert\u00ae<\/strong><br data-start=\"208\" data-end=\"211\" \/><strong data-start=\"211\" data-end=\"228\">Generic Name:<\/strong> Osimertinib<br data-start=\"240\" data-end=\"243\" \/><strong data-start=\"243\" data-end=\"256\">Strength:<\/strong> 80 mg<br data-start=\"262\" data-end=\"265\" \/><strong data-start=\"265\" data-end=\"281\">Dosage Form:<\/strong> Tablet<br data-start=\"288\" data-end=\"291\" \/><strong data-start=\"291\" data-end=\"304\">Category:<\/strong> Targeted Anticancer Therapy<br data-start=\"332\" data-end=\"335\" \/><strong data-start=\"335\" data-end=\"347\">TG Name:<\/strong> Anticancer (EGFR Tyrosine Kinase Inhibitor)<br data-start=\"391\" data-end=\"394\" \/><strong data-start=\"394\" data-end=\"405\">Status:<\/strong> Prescription Only Medicine<\/p>\n<p data-start=\"436\" data-end=\"756\"><strong data-start=\"436\" data-end=\"460\">1. What is Osimert\u00ae?<\/strong><br data-start=\"460\" data-end=\"463\" \/>Osimert\u00ae is a tablet containing Osimertinib INN 80 mg. It is used for the treatment of non-small cell lung cancer (NSCLC) with EGFR mutations. It works by inhibiting EGFR tyrosine kinase activity, helping to stop cancer cell growth and spread. To be used as directed by a registered physician.<\/p>\n","protected":false},"featured_media":100,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[19,22],"product_tag":[],"class_list":{"0":"post-99","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-oncology","7":"product_cat-specialized-product","9":"first","10":"instock","11":"shipping-taxable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product\/99","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/comments?post=99"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/media\/100"}],"wp:attachment":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/media?parent=99"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_brand?post=99"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_cat?post=99"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_tag?post=99"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}