{"id":272,"date":"2026-04-24T19:34:14","date_gmt":"2026-04-24T19:34:14","guid":{"rendered":"https:\/\/asceticit.shop\/wp2\/?post_type=product&#038;p=272"},"modified":"2026-04-26T09:38:26","modified_gmt":"2026-04-26T09:38:26","slug":"nivorest-40","status":"publish","type":"product","link":"https:\/\/asceticit.shop\/wp2\/product\/nivorest-40\/","title":{"rendered":"Nivorest 40"},"content":{"rendered":"<p data-start=\"755\" data-end=\"1015\"><strong data-start=\"755\" data-end=\"779\">1. Product Overview:<\/strong><br data-start=\"779\" data-end=\"782\" \/>Nivorest\u00ae is an injectable formulation of Nivolumab, a monoclonal antibody used in immuno-oncology for the treatment of multiple advanced malignancies, including non-small cell lung cancer, melanoma, renal cell carcinoma, and others.<\/p>\n<p data-start=\"1017\" data-end=\"1121\"><strong data-start=\"1017\" data-end=\"1036\">2. Composition:<\/strong><br data-start=\"1036\" data-end=\"1039\" \/>Active Ingredient: Nivolumab | Dosage Form: Injection (Concentrate for Infusion)<\/p>\n<p data-start=\"1123\" data-end=\"1210\"><strong data-start=\"1123\" data-end=\"1152\">3. Pharmacological Class:<\/strong><br data-start=\"1152\" data-end=\"1155\" \/>Programmed Death-1 (PD-1) Immune Checkpoint Inhibitor<\/p>\n<p data-start=\"1212\" data-end=\"1446\"><strong data-start=\"1212\" data-end=\"1239\">4. Mechanism of Action:<\/strong><br data-start=\"1239\" data-end=\"1242\" \/>Nivolumab blocks the PD-1 receptor on T-cells, preventing cancer cells from evading immune detection. This enhances T-cell mediated immune response against tumor cells, leading to cancer cell destruction.<\/p>\n<p data-start=\"1448\" data-end=\"1612\"><strong data-start=\"1448\" data-end=\"1467\">5. Indications:<\/strong><br data-start=\"1467\" data-end=\"1470\" \/>Non-small cell lung cancer (NSCLC) | Melanoma | Renal cell carcinoma | Hodgkin lymphoma | Head and neck cancer | Other advanced malignancies<\/p>\n<p data-start=\"1614\" data-end=\"1813\"><strong data-start=\"1614\" data-end=\"1645\">6. Dosage &amp; Administration:<\/strong><br data-start=\"1645\" data-end=\"1648\" \/>As prescribed by oncologist | Intravenous infusion only | Administered in hospital\/clinical setting | Dose and schedule depend on cancer type and patient condition<\/p>\n<p data-start=\"1815\" data-end=\"2016\"><strong data-start=\"1815\" data-end=\"1840\">7. Clinical Benefits:<\/strong><br data-start=\"1840\" data-end=\"1843\" \/>Enhances immune system response against cancer | Improves survival in advanced cancers | Effective in multiple tumor types | Provides durable response in selected patients<\/p>\n<p data-start=\"2018\" data-end=\"2094\"><strong data-start=\"2018\" data-end=\"2043\">8. Contraindications:<\/strong><br data-start=\"2043\" data-end=\"2046\" \/>Hypersensitivity to Nivolumab or any component<\/p>\n<p data-start=\"2096\" data-end=\"2290\"><strong data-start=\"2096\" data-end=\"2115\">9. Precautions:<\/strong><br data-start=\"2115\" data-end=\"2118\" \/>Risk of immune-related adverse reactions (lung, liver, colon, endocrine disorders) | Requires regular monitoring of organ function | Use under strict oncology supervision<\/p>\n<p data-start=\"2292\" data-end=\"2414\"><strong data-start=\"2292\" data-end=\"2318\">10. Drug Interactions:<\/strong><br data-start=\"2318\" data-end=\"2321\" \/>May interact with immunosuppressants such as corticosteroids, potentially reducing efficacy<\/p>\n<p data-start=\"2416\" data-end=\"2591\"><strong data-start=\"2416\" data-end=\"2444\">11. Special Populations:<\/strong><br data-start=\"2444\" data-end=\"2447\" \/>Pregnancy: Not recommended | Lactation: Not recommended | Pediatric: Use only under specialist guidance | Elderly: Requires careful monitoring<\/p>\n<p data-start=\"2593\" data-end=\"2737\"><strong data-start=\"2593\" data-end=\"2617\">12. Adverse Effects:<\/strong><br data-start=\"2617\" data-end=\"2620\" \/>Fatigue | Skin rash | Diarrhea | Immune-related pneumonitis | Hepatitis | Endocrine disorders (thyroid dysfunction)<\/p>\n<p data-start=\"2739\" data-end=\"2871\"><strong data-start=\"2739\" data-end=\"2766\">13. Storage Conditions:<\/strong><br data-start=\"2766\" data-end=\"2769\" \/>Store at 2\u00b0C\u20138\u00b0C (refrigerated) | Do not freeze | Protect from light | Keep out of reach of children<\/p>\n<p data-start=\"2873\" data-end=\"2910\"><strong data-start=\"2873\" data-end=\"2891\">14. Packaging:<\/strong><br data-start=\"2891\" data-end=\"2894\" \/>Injection vial<\/p>\n<p data-start=\"2912\" data-end=\"2965\"><strong data-start=\"2912\" data-end=\"2933\">15. Manufacturer:<\/strong><br data-start=\"2933\" data-end=\"2936\" \/>Everest Pharmaceutical Ltd.<\/p>\n","protected":false},"excerpt":{"rendered":"<p data-start=\"147\" data-end=\"388\"><strong data-start=\"147\" data-end=\"164\">Generic Name:<\/strong> Nivolumab<br data-start=\"174\" data-end=\"177\" \/><strong data-start=\"177\" data-end=\"190\">Strength:<\/strong> 40 mg<br data-start=\"196\" data-end=\"199\" \/><strong data-start=\"199\" data-end=\"215\">Dosage Form:<\/strong> Injection (Concentrate for Infusion)<br data-start=\"252\" data-end=\"255\" \/><strong data-start=\"255\" data-end=\"268\">Category:<\/strong> Immuno-Oncology Therapy (Checkpoint Inhibitor)<br data-start=\"315\" data-end=\"318\" \/><strong data-start=\"318\" data-end=\"330\">TG Name:<\/strong> PD-1 Inhibitor<br data-start=\"345\" data-end=\"348\" \/><strong data-start=\"348\" data-end=\"359\">Status:<\/strong> Prescription Only Medicine<\/p>\n<hr data-start=\"390\" data-end=\"393\" \/>\n<h2 data-section-id=\"16ih8dt\" data-start=\"395\" data-end=\"421\"><span role=\"text\"><strong data-start=\"398\" data-end=\"419\">Short Description<\/strong><\/span><\/h2>\n<p data-start=\"422\" data-end=\"728\">Nivorest\u00ae 40 mg is an immunotherapy anticancer injection containing Nivolumab, used for the treatment of various advanced cancers including lung cancer, melanoma, and kidney cancer. It works by enhancing the body\u2019s immune system to recognize and destroy cancer cells. To be used under oncology supervision.<\/p>\n","protected":false},"featured_media":336,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[23,30],"product_tag":[],"class_list":{"0":"post-272","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-general-products","7":"product_cat-immunomodulators","9":"first","10":"instock","11":"shipping-taxable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product\/272","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/comments?post=272"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/media\/336"}],"wp:attachment":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/media?parent=272"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_brand?post=272"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_cat?post=272"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_tag?post=272"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}