{"id":270,"date":"2026-04-24T19:28:05","date_gmt":"2026-04-24T19:28:05","guid":{"rendered":"https:\/\/asceticit.shop\/wp2\/?post_type=product&p=270"},"modified":"2026-04-26T16:51:06","modified_gmt":"2026-04-26T16:51:06","slug":"tofaxen","status":"publish","type":"product","link":"https:\/\/asceticit.shop\/wp2\/product\/tofaxen\/","title":{"rendered":"Tofaxen"},"content":{"rendered":"

1. Product Overview:<\/strong>
Tofaxen\u00ae is a tablet formulation of Tofacitinib, a Janus kinase (JAK) inhibitor used in the treatment of autoimmune and inflammatory diseases such as rheumatoid arthritis.<\/p>\n

2. Composition:<\/strong>
Active Ingredient: Tofacitinib | Dosage Form: Tablet<\/p>\n

3. Pharmacological Class:<\/strong>
Janus Kinase (JAK) Inhibitor \/ Targeted DMARD<\/p>\n

4. Mechanism of Action:<\/strong>
Tofacitinib selectively inhibits JAK enzymes, blocking intracellular signaling pathways involved in inflammation and immune response, thereby reducing cytokine activity and joint damage.<\/p>\n

5. Indications:<\/strong>
Rheumatoid arthritis | Psoriatic arthritis | Ulcerative colitis | Other autoimmune inflammatory disorders<\/p>\n

6. Dosage & Administration:<\/strong>
As prescribed by physician | Oral use | Usually taken once or twice daily depending on condition | Can be taken with or without food<\/p>\n

7. Clinical Benefits:<\/strong>
Reduces joint pain and swelling | Slows disease progression | Improves physical function | Provides targeted immune control<\/p>\n

8. Contraindications:<\/strong>
Hypersensitivity to Tofacitinib | Active severe infections | Severe hepatic impairment<\/p>\n

9. Precautions:<\/strong>
Increased risk of infections | Monitor blood counts and liver function regularly | Risk of thrombosis in some patients | Use under specialist supervision<\/p>\n

10. Drug Interactions:<\/strong>
May interact with strong immunosuppressants, CYP3A4 inhibitors, and inducers, altering drug levels<\/p>\n

11. Special Populations:<\/strong>
Pregnancy: Not recommended unless necessary | Lactation: Not recommended | Pediatric: Safety not fully established | Elderly: Increased risk of infections<\/p>\n

12. Adverse Effects:<\/strong>
Upper respiratory infections | Headache | Diarrhea | Increased cholesterol levels | Nausea | Risk of serious infections<\/p>\n

13. Storage Conditions:<\/strong>
Store below 30\u00b0C | Protect from light and moisture | Keep out of reach of children<\/p>\n

14. Packaging:<\/strong>
Tablet in blister pack<\/p>\n

15. Manufacturer:<\/strong>
Everest Pharmaceutical Ltd.<\/p>\n","protected":false},"excerpt":{"rendered":"

Generic Name:<\/strong> Tofacitinib
Strength:<\/strong> 5 mg \/ 10 mg (as available)
Dosage Form:<\/strong> Tablet
Category:<\/strong> Janus Kinase (JAK) Inhibitor \/ Immunomodulator
TG Name:<\/strong> Targeted DMARD (Disease Modifying Anti-Rheumatic Drug)
Status:<\/strong> Prescription Only Medicine<\/p>\n

\n

Short Description<\/strong><\/span><\/h2>\n

Tofaxen\u00ae is a targeted immunomodulatory medicine containing Tofacitinib, used for the treatment of rheumatoid arthritis and other autoimmune conditions. It works by inhibiting Janus kinase (JAK) pathways, helping to reduce inflammation, pain, and joint damage. To be used under specialist supervision.<\/p>\n","protected":false},"featured_media":364,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[23,30],"product_tag":[],"class_list":{"0":"post-270","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-general-products","7":"product_cat-immunomodulators","9":"first","10":"instock","11":"shipping-taxable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product\/270","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/comments?post=270"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/media\/364"}],"wp:attachment":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/media?parent=270"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_brand?post=270"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_cat?post=270"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_tag?post=270"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}