{"id":135,"date":"2026-04-14T17:06:25","date_gmt":"2026-04-14T17:06:25","guid":{"rendered":"https:\/\/asceticit.shop\/wp2\/?post_type=product&#038;p=135"},"modified":"2026-04-28T21:22:38","modified_gmt":"2026-04-28T21:22:38","slug":"imaxen-400","status":"publish","type":"product","link":"https:\/\/asceticit.shop\/wp2\/product\/imaxen-400\/","title":{"rendered":"Imaxen 400"},"content":{"rendered":"<p data-start=\"641\" data-end=\"859\"><strong data-start=\"641\" data-end=\"665\">1. Product Overview:<\/strong> Imaxen 400\u00ae is a tyrosine kinase inhibitor containing Imatinib, used in the treatment of certain blood and solid tumors including chronic myeloid leukemia and gastrointestinal stromal tumors.<\/p>\n<p data-start=\"861\" data-end=\"955\"><strong data-start=\"861\" data-end=\"880\">2. Composition:<\/strong> Imatinib Mesilate BP equivalent to Imatinib 400 mg | Dosage Form: Tablet<\/p>\n<p data-start=\"957\" data-end=\"1046\"><strong data-start=\"957\" data-end=\"986\">3. Pharmacological Class:<\/strong> Tyrosine Kinase Inhibitor (BCR-ABL, KIT, PDGFR inhibitor)<\/p>\n<p data-start=\"1048\" data-end=\"1254\"><strong data-start=\"1048\" data-end=\"1075\">4. Mechanism of Action:<\/strong> Imatinib selectively inhibits abnormal tyrosine kinase enzymes such as BCR-ABL, KIT, and PDGFR, thereby blocking uncontrolled cell proliferation and inducing cancer cell death.<\/p>\n<p data-start=\"1256\" data-end=\"1454\"><strong data-start=\"1256\" data-end=\"1275\">5. Indications:<\/strong> Chronic myeloid leukemia (CML) | Gastrointestinal stromal tumors (GIST) | Philadelphia chromosome\u2013positive acute lymphoblastic leukemia (Ph+ ALL) | Myeloproliferative disorders<\/p>\n<p data-start=\"1456\" data-end=\"1638\"><strong data-start=\"1456\" data-end=\"1487\">6. Dosage &amp; Administration:<\/strong> As directed by oncology specialist only | Oral use | Usually taken once daily with food and a full glass of water | Dose may vary based on condition<\/p>\n<p data-start=\"1640\" data-end=\"1790\"><strong data-start=\"1640\" data-end=\"1665\">7. Clinical Benefits:<\/strong> Controls cancer cell growth | Improves survival in CML and GIST | Reduces disease progression | Effective targeted therapy<\/p>\n<p data-start=\"1792\" data-end=\"1884\"><strong data-start=\"1792\" data-end=\"1817\">8. Contraindications:<\/strong> Hypersensitivity to Imatinib or any component of the formulation<\/p>\n<p data-start=\"1886\" data-end=\"2043\"><strong data-start=\"1886\" data-end=\"1905\">9. Precautions:<\/strong> Liver function monitoring required | Risk of fluid retention and edema | Blood count monitoring necessary | Use cautiously in pregnancy<\/p>\n<p data-start=\"2045\" data-end=\"2168\"><strong data-start=\"2045\" data-end=\"2071\">10. Drug Interactions:<\/strong> May interact with CYP3A4 inhibitors\/inducers, warfarin, and certain antibiotics or antifungals<\/p>\n<p data-start=\"2170\" data-end=\"2340\"><strong data-start=\"2170\" data-end=\"2198\">11. Special Populations:<\/strong> Not recommended during pregnancy unless clearly necessary | Lactation use under strict medical advice | Elderly patients require monitoring<\/p>\n<p data-start=\"2342\" data-end=\"2452\"><strong data-start=\"2342\" data-end=\"2366\">12. Adverse Effects:<\/strong> Nausea | Edema | Muscle cramps | Fatigue | Rash | Diarrhea | Liver enzyme elevation<\/p>\n<p data-start=\"2454\" data-end=\"2566\"><strong data-start=\"2454\" data-end=\"2481\">13. Storage Conditions:<\/strong> Store below 30\u00b0C | Protect from light and moisture | Keep out of reach of children<\/p>\n<p data-start=\"2568\" data-end=\"2608\"><strong data-start=\"2568\" data-end=\"2586\">14. Packaging:<\/strong> Tablet blister pack<\/p>\n<p data-start=\"2610\" data-end=\"2659\" data-is-last-node=\"\" data-is-only-node=\"\"><strong data-start=\"2610\" data-end=\"2631\">15. Manufacturer:<\/strong> Everest Pharmaceutical Ltd.<\/p>\n","protected":false},"excerpt":{"rendered":"<p data-start=\"24\" data-end=\"291\"><strong data-start=\"24\" data-end=\"41\">Generic Name:<\/strong> Imatinib Mesilate BP (equivalent to Imatinib)<br data-start=\"87\" data-end=\"90\" \/><strong data-start=\"90\" data-end=\"103\">Strength:<\/strong> 400 mg<br data-start=\"110\" data-end=\"113\" \/><strong data-start=\"113\" data-end=\"129\">Dosage Form:<\/strong> Tablet<br data-start=\"136\" data-end=\"139\" \/><strong data-start=\"139\" data-end=\"152\">Category:<\/strong> Antineoplastic \/ Tyrosine Kinase Inhibitor<br data-start=\"195\" data-end=\"198\" \/><strong data-start=\"198\" data-end=\"210\">TG Name:<\/strong> Hematological Cancer Management<br data-start=\"242\" data-end=\"245\" \/><strong data-start=\"245\" data-end=\"256\">Status:<\/strong> Prescription Only Medicine (POM)<\/p>\n<hr data-start=\"293\" data-end=\"296\" \/>\n<h2 data-section-id=\"1pjlvap\" data-start=\"298\" data-end=\"318\">Short Description<\/h2>\n<p data-start=\"320\" data-end=\"618\"><strong data-start=\"320\" data-end=\"335\">Imaxen 400\u00ae<\/strong> is a targeted anticancer medicine containing Imatinib 400 mg, used for the treatment of chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GIST), and other related cancers. It works by blocking abnormal cancer cell growth. To be used only under specialist supervision.<\/p>\n","protected":false},"featured_media":393,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[21,22],"product_tag":[],"class_list":{"0":"post-135","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-hematology","7":"product_cat-specialized-product","9":"first","10":"instock","11":"shipping-taxable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product\/135","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/comments?post=135"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/media\/393"}],"wp:attachment":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/media?parent=135"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_brand?post=135"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_cat?post=135"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_tag?post=135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}