{"id":117,"date":"2026-04-14T16:21:23","date_gmt":"2026-04-14T16:21:23","guid":{"rendered":"https:\/\/asceticit.shop\/wp2\/?post_type=product&#038;p=117"},"modified":"2026-04-26T09:04:33","modified_gmt":"2026-04-26T09:04:33","slug":"ibruxen","status":"publish","type":"product","link":"https:\/\/asceticit.shop\/wp2\/product\/ibruxen\/","title":{"rendered":"Ibruxen"},"content":{"rendered":"<ul>\n<li data-section-id=\"1sr8x9w\" data-start=\"622\" data-end=\"838\">Product Overview: Ibruxen\u00ae is a Bruton\u2019s tyrosine kinase (BTK) inhibitor containing Ibrutinib, used in the treatment of specific B-cell malignancies including chronic lymphocytic leukemia and mantle cell lymphoma.<\/li>\n<li data-section-id=\"byr2un\" data-start=\"840\" data-end=\"899\">Composition: Ibrutinib INN 140 mg | Dosage Form: Capsule<\/li>\n<li data-section-id=\"14sgioa\" data-start=\"901\" data-end=\"997\">Pharmacological Class: Bruton\u2019s Tyrosine Kinase (BTK) Inhibitor \/ Targeted Anticancer Therapy<\/li>\n<li data-section-id=\"1338q9l\" data-start=\"999\" data-end=\"1181\">Mechanism of Action: Ibrutinib irreversibly inhibits BTK, a key enzyme in B-cell receptor signaling pathways, leading to inhibition of malignant B-cell proliferation and survival.<\/li>\n<li data-section-id=\"6pebp0\" data-start=\"1183\" data-end=\"1331\">Indications: Chronic lymphocytic leukemia (CLL) | Small lymphocytic lymphoma (SLL) | Mantle cell lymphoma (MCL) | Waldenstr\u00f6m\u2019s macroglobulinemia<\/li>\n<li data-section-id=\"lj3c38\" data-start=\"1333\" data-end=\"1485\">Dosage &amp; Administration: As directed by oncology specialist only | Oral use | Usually taken once daily | Capsule should be swallowed whole with water<\/li>\n<li data-section-id=\"7ss7uo\" data-start=\"1487\" data-end=\"1640\">Clinical Benefits: Slows progression of blood cancers | Reduces cancer cell growth | Improves disease control | Prolongs survival in eligible patients<\/li>\n<li data-section-id=\"1w2vm55\" data-start=\"1642\" data-end=\"1729\">Contraindications: Hypersensitivity to Ibrutinib or any component of the formulation<\/li>\n<li data-section-id=\"1tq825h\" data-start=\"1731\" data-end=\"1899\">Precautions: Risk of bleeding | Risk of infection | Monitor blood counts regularly | Use cautiously in liver impairment | Avoid in pregnancy unless clearly necessary<\/li>\n<li data-section-id=\"1eaulv5\" data-start=\"1901\" data-end=\"2015\">Drug Interactions: May interact with strong CYP3A inhibitors\/inducers, anticoagulants, and antiplatelet agents<\/li>\n<li data-section-id=\"11s9uio\" data-start=\"2017\" data-end=\"2164\">Special Populations: Not recommended during pregnancy and lactation unless clearly advised by oncologist | Elderly use under strict supervision<\/li>\n<li data-section-id=\"q0kro0\" data-start=\"2166\" data-end=\"2287\">Adverse Effects: Diarrhea | Fatigue | Bruising | Neutropenia | Anemia | Risk of bleeding | Atrial fibrillation (rare)<\/li>\n<li data-section-id=\"1c9kz1n\" data-start=\"2289\" data-end=\"2395\">Storage Conditions: Store below 30\u00b0C | Protect from light and moisture | Keep out of reach of children<\/li>\n<li data-section-id=\"1jlx80o\" data-start=\"2397\" data-end=\"2432\">Packaging: Capsule blister pack<\/li>\n<li data-section-id=\"f9iv2p\" data-start=\"2434\" data-end=\"2479\" data-is-last-node=\"\">Manufacturer: Everest Pharmaceutical Ltd.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p data-start=\"24\" data-end=\"267\"><strong data-start=\"24\" data-end=\"41\">Generic Name:<\/strong> Ibrutinib INN<br data-start=\"55\" data-end=\"58\" \/><strong data-start=\"58\" data-end=\"71\">Strength:<\/strong> 140 mg<br data-start=\"78\" data-end=\"81\" \/><strong data-start=\"81\" data-end=\"97\">Dosage Form:<\/strong> Capsule<br data-start=\"105\" data-end=\"108\" \/><strong data-start=\"108\" data-end=\"121\">Category:<\/strong> Antineoplastic \/ Targeted Therapy (BTK Inhibitor)<br data-start=\"171\" data-end=\"174\" data-is-only-node=\"\" \/><strong data-start=\"174\" data-end=\"186\">TG Name:<\/strong> Hematological Cancer Management<br data-start=\"218\" data-end=\"221\" \/><strong data-start=\"221\" data-end=\"232\">Status:<\/strong> Prescription Only Medicine (POM)<\/p>\n<hr data-start=\"269\" data-end=\"272\" \/>\n<h2 data-section-id=\"1pjlvap\" data-start=\"274\" data-end=\"294\">Short Description<\/h2>\n<p data-start=\"296\" data-end=\"599\"><strong data-start=\"296\" data-end=\"308\">Ibruxen\u00ae<\/strong> is a targeted anticancer medicine containing Ibrutinib INN 140 mg, used for the treatment of certain blood cancers such as chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. It works by inhibiting cancer cell growth and spread. To be used only under strict specialist supervision.<\/p>\n","protected":false},"featured_media":328,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[19,22],"product_tag":[],"class_list":{"0":"post-117","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-oncology","7":"product_cat-specialized-product","9":"first","10":"instock","11":"shipping-taxable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product\/117","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/comments?post=117"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/media\/328"}],"wp:attachment":[{"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/media?parent=117"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_brand?post=117"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_cat?post=117"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/asceticit.shop\/wp2\/wp-json\/wp\/v2\/product_tag?post=117"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}