Description

1. Product Overview: Thalamia® is an immunomodulatory and anticancer agent containing Thalidomide, used in the management of multiple myeloma and selected inflammatory disorders.

2. Composition: Thalidomide USP 100 mg | Dosage Form: Capsule

3. Pharmacological Class: Immunomodulatory / Antineoplastic Agent

4. Mechanism of Action: Thalidomide modulates the immune system by inhibiting pro-inflammatory cytokines (such as TNF-α) and reducing angiogenesis, thereby suppressing abnormal immune activity and tumor growth.

5. Indications: Multiple myeloma | Erythema nodosum leprosum (ENL) | Selected immunological disorders as prescribed

6. Dosage & Administration: As directed by oncology or specialist physician only | Oral use | Usually taken once daily at bedtime | Dose strictly individualized

7. Clinical Benefits: Helps control abnormal immune activity | Supports treatment of multiple myeloma | Reduces inflammation in ENL | Improves disease control in selected conditions

8. Contraindications: Pregnancy (strictly contraindicated) | Hypersensitivity to Thalidomide or any component of the formulation

9. Precautions: Highly teratogenic (requires strict pregnancy prevention program) | Risk of peripheral neuropathy | Sedation and dizziness may occur | Regular monitoring required

10. Drug Interactions: May enhance sedation with CNS depressants | Caution with other immunosuppressive or neurotoxic drugs

11. Special Populations: Absolutely contraindicated in pregnancy and must not be used without strict contraceptive measures | Use in elderly under close supervision

12. Adverse Effects: Drowsiness | Constipation | Peripheral neuropathy | Rash | Dizziness | Risk of thrombosis

13. Storage Conditions: Store below 30°C | Protect from light and moisture | Keep out of reach of children

14. Packaging: Capsule blister pack

15. Manufacturer: Everest Pharmaceutical Ltd.